Criteria for Diagnoses of Atopic Dermatitis

Major Features (Must Have Three or More)
Pruritus
Typical morphology and distribution
Flexural lichenification in adults
Facial and extensor involvement in infants and children
Dermatitis—chronically or chronically relapsing
Personal or family history or atopy—asthma, allergic rhinitis, atopic dermatitis
Minor Features (Must Have Three or More)
Cataracts (anterior-subcapsular)
Cheilitis
Conjunctivitis—recurrent
Eczema—perifollicular accentuation
Facial pallor/facial erythema
Food intolerance
Hand dermatitis—nonallergic, irritant
Ichthyosis
IgE—elevated
Immediate (Type 1) skin test reactivity
Infections (cutaneous)—Staphylococcus aureus, herpes simplex
Infraorbital fold (Dennie-Morgan lines)
Itching when sweating
Keratoconus
Keratosis pilaris
Nipple dermatitis
Orbital darkening
Palmar hyperlinearity
Pityriasis alba
White dermographism
Wool intolerance
Xerosis





Data from Roth HL: Int J Dermatol 1987; 26:139; Hanifin JM, Rajka G: Acta Derm Venereol (Stockh) 1980; 92(suppl):44; and Hanifin JM, Lobitz WC Jr: Arch Dermatol 1977; 113:663.